The Role of Omega-6 in Melanoma and Skin Cancers


Hello, dear readers! Today, we delve into a hot topic—Omega-6 fatty acids and their suspected relationship with melanoma and skin cancers. While much of the information we currently have is anecdotal, it's bolstered by some fascinating studies on adipose tissue. A large part of today's discussion is inspired by Tucker Goodrich, a researcher who has dedicated a significant amount of time to understanding the impact of Omega-6 fatty acids on human health. He's been on the Fundamental Health podcast twice, and we'll be exploring some of his findings today.


Omega-6 fatty acids are essential nutrients, meaning they are necessary for human health, but the body can't produce them. You have to get them through food. Sources include nuts and seeds. The challenge, however, is that modern diets are disproportionately rich in Omega-6 (because of the recent addition of highly processed vegetable oils, Watch this video, it may change your life today!), causing an imbalance that has been implicated in a variety of health issues.

Tucker Goodrich is a name you may have heard if you've dabbled in nutritional research, particularly around fats. He has shared his extensive knowledge on Omega-6 fatty acids. The insights he brings are often eye-opening and back up many of the suspicions that people have about the typical Western diet.

Anecdotal Observations

Tucker Goodrich's N=1 Experiment


N=1 on Omega-6 and Sunburn: Can Sunburn be Reduced?


Tucker conducted what's known as an N=1 experiment, focusing solely on his own experiences. He spent significant amounts of time in the sun last summer, specifically doing three to four-hour runs in Texas. What's astonishing is that despite this extreme sun exposure, he didn't get sunburned.

Public Feedback

Whenever the topic of sunburn and Omega-6 is broached on social platforms, the response is usually overwhelming. Many people seem to agree, at least anecdotally, that changing your diet could result in a decreased susceptibility to sunburn.

Additional Accounts

Other people have chimed in with their own experiences, reporting that shifting to an animal-based diet—rich in organs, meat, honey, fruit, and raw dairy—resulted in significantly reduced episodes of sunburn.

Diet Change Sunburn Susceptibility
Increased Omega-6 High
"Balanced" Diet Moderate
Animal-Based Diet Low

Scientific Mechanisms

Breakdown of Omega-6 in the Skin

When there is an excess of Omega-6 in the skin, it tends to break down into toxins when exposed to UV/blue light. This breakdown triggers inflammation and cell death, contributing to the risk of skin conditions including cancers.

Correlation with Animal-Based Diet

Those who have switched to an animal-based diet, rich in organs, meat, fruit, honey, and raw dairy, have reported lesser incidents of sunburn. The mechanistic probability behind this lies in how such diets could potentially be reducing OXLAMs (Oxidized linoleic acid metabolites)—byproducts of Omega-6 fatty acids.

Role of Linoleic Acid

Linoleic acid have been observed in various other studies to have links with obesity, pregnancy complications, and even cardiac dysfunction. They also contribute to oxidative stress markers and atheromas (a fatty material that builds up inside your arteries).

Experiment Details

Tucker Goodrich wasn't using any sunscreen during his lengthy exposures to the sun. This leads to further questions about the role of sunscreen, but that's a topic for the next blog. What's intriguing here is that Tucker's cardio choices also come into play. He was doing long runs, and we hope he was focusing on forefoot striking rather than heel striking to avoid potential health complications.

Linoleic Acid Research

The research on linoleic acid is expansive and somewhat unsettling. Studies have shown that reducing linoleic acid can reduce OXLAMs in rats and is related to cardiac dysfunction. The depth of this research indicates that we're skirting the surface of a very intricate issue that could have widespread health implications.

The Need for More Research

While the anecdotes and mechanisms discussed offer compelling narratives, there is a dire need for more empirical research. We need controlled studies to ascertain the impact of Omega-6 fatty acids on skin health and cancer risks.


The relationship between Omega-6 fatty acids and skin health, specifically melanoma and other skin cancers, is complex and not yet fully understood. However, the anecdotal evidence, supported by Tucker Goodrich's observations and existing research, indicates that there may be a connection worth investigating. We can't ignore the mechanistic probability linking Omega-6 fatty acids to skin issues. However, as intriguing as these findings are, it's crucial to approach them with scientific rigor through well-designed studies.

Call to Action

Stay updated with new research on this subject and consider sharing your own experiences or observations by sending us a message here.

By offering this comprehensive look into the role of Omega-6 fatty acids in melanoma and skin cancers, we hope to encourage a balanced and research-driven dialogue on the subject. Thank you for reading.